Explore the success stories, client collaborations, and scientific contributions that highlight our profound impact across the industry.
"I am delighted to share that CSIR-CDRI and Sravathi AI have been collaborating on a target of common interest in the area of cancer. Sravathi’s expertise in applying artificial intelligence to drug discovery complements CDRI’s strengths in biology and chemistry. Our goal is to jointly accelerate the identification of novel, effective, and safe cancer therapeutics."
"I had one of the best customer service experiences with Sravathi AI Technologies Ltd. From the moment I reached out, the representative was friendly, attentive, and truly committed to resolving our Domain related issue. Not only did they listen carefully to my concerns, but they also followed up promptly with updates and went above and beyond to make sure I was satisfied. It’s rare to find a team that genuinely cares about its customers, but this one exceeded all my expectations. I left the interaction feeling valued, respected, and confident in continuing to do business with them. Truly a gold standard in customer care!"
“Our collaboration with Sravathi AI has been highly productive and professional. Their team brings strong scientific expertise and an impressive capacity for execution, consistently advancing novel compounds across multiple oncology targets. Through structured biweekly meetings, we have observed steady progress, including the successful synthesis and delivery of approximately ten compounds for testing. We value their rigor, responsiveness, and commitment to high-quality science, and view Sravathi AI as a trusted partner in our translational research efforts.”
Ensuring drug purity and safety requires anticipating impurities before they appear in the lab. This case study showcases how our Chemistry AI platform applies predictive modeling to identify unknown impurities and their formation pathways early in development, enabling proactive process adjustments that save time, reduce risk, and ensure higher-quality outcomes.
This case study demonstrates how our platform was used to optimize the Suzuki coupling reaction for a key intermediate of the drug Atazanavir. The goal was to identify the optimal reaction conditions to achieve the highest possible yield.
In modern drug development, choosing the right synthetic route is crucial. Using our Chemistry AI platform powered by quantum calculations, we can predict reaction feasibility upfront, compare pathways, and identify the most promising route. This approach streamlines decision-making, reduces trial-and-error, and accelerates experimental validation.
This case study highlights how our platform was used to optimize the synthesis of the drug Nilotinib. It demonstrates the power of AI in transforming a complex, multi-step process into a streamlined, commercially viable route with fewer steps and more readily available starting materials. The our Chemistry AI platform, unlike traditional methods, rapidly identifies and optimizes multiple synthetic routes simultaneously.
Background: Pancreatic cancer is highly aggressive and treatment-resistant, with limited options and poor survival rates. Traditional drug discovery has made limited progress, underscoring the need for innovative approaches.
At Sravathi AI, By integrating Density Functional Theory (DFT) and Molecular Dynamics (MD) simulations, we uncover molecular-level insights that guide the rational design of cosmetic ingredients and formulations. This approach moves beyond conventional trial-and-error experimentation, enabling predictive, science-backed strategies that improve product performance, stability, and safety.
A small-molecule compound that had previously failed in Phase 3 trials for a non-oncology indication presented an opportunity for repurposing due to its favorable safety profile and drug-like properties. Given the urgent need for new treatments in pancreatic cancer, we applied our AI- and physics-based platform to identify new potential oncology applications for the molecule.
This research introduces the Molecular Glue-Design-Evaluator (MOLDE), an innovative computational method designed for the rational design of molecular glues. By using a combination of techniques, including new chemical entity generation, optimization, and molecular dynamics simulations, MOLDE aims to accelerate the discovery process and pave the way for targeting previously inaccessible proteins.
Our research introduces the PROTAC-Design-Evaluator (PRODE), an advanced computational method for the in-silico design of these complex molecules. This innovative approach allows us to rapidly and effectively design PROTACs for new systems, such as the FGFR1-MDM2 complex, offering a promising path toward new therapeutic strategies.
It's an exciting time for Sravathi Ai! We're thrilled to announce our selection as Regional Finalists in the prestigious L'Oréal Big Bang India Competition. This recognition is a testament to our team's dedication to innovation and our commitment to pushing boundaries. We look forward to showcasing our progress and competing at the regional level.
Leveraging Sravathi’s AI-driven drug-discovery platform and CSIR-CDRI’s extensive cancer R&D infrastructure, this collaboration aims to rapidly design, synthesize, and biologically evaluate novel anti-cancer chemical entities. The joint effort promises speed, cost-efficiency, and a powerful strategic push toward treatments for cancers with limited therapeutic options
In a May 2023, IIT Madras - Shaastra feature, Sravathi AI’s Kishan Gurram underscores that around 9,000–10,000 molecules already known to be safe in humans offer a powerful avenue for drug repurposing. By leveraging AI and ML to screen and prioritize candidates, Sravathi aims to accelerate identification of high-potential therapies for new indications, vastly reducing development time and cost